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XRCC7 rs#7003908 Polymorphism and Helicobacter pylori Infection-Related Gastric Antrum Adenocarcinoma
Chao Wang,Xiao-Ying Huang,Jin-Guang Yao,Bing-Chen Huang,Cen-Han Huang,Pinhu Liao,Xi-Dai Long
International Journal of Genomics , 2013, DOI: 10.1155/2013/124612
Abstract: The X-ray repair cross-complementing group 7 (XRCC7) plays a key role in DNA repair that protects against genetic instability and carcinogenesis. To determine whether XRCC7 rs#7003908 polymorphism (XRCC7P) is associated with Helicobacter pylori (H. pylori) infection-related gastric antrum adenocarcinoma (GAA) risk, we conducted a hospital-based case-control study, including 642 patients with pathologically confirmed GAA and 927 individually matched controls without any evidence of tumours or precancerous lesions, among Guangxi population. Increased risks of GAA were observed for individuals with cagA positive (odds ratio (OR) 6.38; 95% confidence interval (CI) 5.03–8.09). We also found that these individuals with the genotypes of XRCC7 rs#7003908 G alleles (XRCC7-TG or -GG) featured increasing risk of GAA (ORs 2.80 and 5.13, resp.), compared with the homozygote of XRCC7 rs#7003908 T alleles (XRCC7-TT). GAA risk, moreover, did appear to differ more significantly among individuals featuring cagA-positive status, whose adjusted ORs (95% CIs) were 15.74 (10.89–22.77) for XRCC7-TG and 38.49 (22.82–64.93) for XRCC7-GG, respectively. Additionally, this polymorphism multiplicatively interacted with XRCC3 codon 241 polymorphism with respect to HCC risk ( ). These results suggest that XRCC7P may be associated with the risk of Guangxiese GAA related to cagA. 1. Introduction Gastric cancer is the fourth most common cancer worldwide and the second most common cause of death from cancer [1, 2]. The predominant type of this tumor in Guangxi Zhuang Autonomous Region is gastric antrum adenocarcinoma (GAA) [3]. Clinic-epidemiological evidence suggests that Helicobacter pylori (H. pylori) infection is a major risk factor [4, 5]. Increasing evidence has shown that cagA protein, an important H. pylori-produced virulent factor for gastric mucosa injury, could induce many kinds of DNA damage including DNA base damage, DNA double-strand break (DSBs), and oxidative damage [5–10]. Among these DNA damages, DSBs are the most detrimental form [11, 12], because they may lead to both chromosomal breakage and rearrangement and ultimately lead to tumorigenesis of cancers such as GAA. DNA repair gene “X-ray repair cross-complementing group 7” (XRCC7) is necessary for DNA ligation in the nonhomologous end-joining (NHEJ) pathway, which is responsible for repairing most double-strand breaks [13, 14]. Recently, several studies have shown that XRCC7 rs#7003908 polymorphism (XRCC7P) may be associated with DNA repair capacity and tumor risk [15–17]. However, the association between this
Measurements of Nighttime Nitrate Radical Concentrations in the Atmosphere by Long-Path Differential Optical Absorption Spectroscopy
LI Suwen,LIU Wenqing,XIE Pinhu,LI Ang,QIN Min,DOU Ke,
LI Suwen
,LIU Wenqing,XIE Pinhu,LI Ang,QIN Min,DOU Ke

大气科学进展 , 2007,
Abstract: The long-path differential optical absorption spectroscopy (LP-DOAS) technique was developed to measure nighttime atmospheric nitrate radical (NO3) concentrations. An optimized retrieval method, resulting in a small residual structure and low detection limits, was developed to retrieve NO3. The time series of the NO3 concentration were collected from 17 to 24 March, 2006, where a nighttime average value of 15.8 ppt was observed. The interfering factors and errors are also discussed. These results indicate that the DOAS technique provides an essential tool for the quantification of NO3 concentration and in the study of its effects upon nighttime chemistry.
Intercomparison of Nox,SO2,O3,and Aromatic Hydrocarbons Measured by a Commercial DOAS System and Traditional Point Monitoring Techniques
Intercomparison of NOx, SO2, O3, and Aromatic Hydrocarbons Measured by a Commercial DOAS System and Traditional Point Monitoring Techniques

XIE Pinhu,LIU Wenqing,FU Qiang,WANG Ruibin,LIU Jianguo,WEI Qingnong,
XIE Pinhu
,LIU Wenqing,FU Qiang,WANG Ruibin,LIU Jianguo,WEI Qingnong

大气科学进展 , 2004,
Abstract: A field-based intercomparison study of a commercial Differential Optical Absorption Spectroscopy (DOAS) instrument (OPSIS AB, Sweden) and different point-sample monitoring techniques (PM, based on an air monitoring station, an air monitoring vehicle, and various chemical methods) was conducted in Beijing from October 1999 to January 2000. The mixing ratios of six trace gases including NO, NO2, SO2,O3, benzene, and toluene were monitored continuously during the four months. A good agreement between the DOAS and PM data was found for NO2 and SO2. However, the concentrations of benzene, toluene,and NO obtained by DOAS were significantly lower than those measured by the point monitors. The ozone levels monitored by the DOAS were generally higher than those measured by point monitors. These results may be attributed to a strong vertical gradient of the NO-O3-NO2 system and of the aromatics at the measurement site. Since the exact data evaluation algorithm is not revealed by the manufacturer of the DOAS system, the error in the DOAS analysis can also not be excluded.
The Rough Method for Spatial Data Subzone Similarity Measurement  [PDF]
Weihua Liao
Journal of Geographic Information System (JGIS) , 2012, DOI: 10.4236/jgis.2012.41006
Abstract: There are two methods for GIS similarity measurement problem, one is cross-coefficient for GIS attribute similarity measurement, and the other is spatial autocorrelation that is based on spatial location. These methods can not calculate subzone similarity problem based on universal background. The rough measurement based on membership function solved this problem well. In this paper, we used rough sets to measure the similarity of GIS subzone discrete data, and used neighborhood rough sets to calculate continuous data’s upper and lower approximation. We used neighborhood particle to calculate membership function of continuous attribute, then to solve continuous attribute’s subzone similarity measurement problem.
Discussion on Dry Cough with Yellow Greasy Coating  [PDF]
Xian Liao
Chinese Medicine (CM) , 2012, DOI: 10.4236/cm.2012.31008
Abstract: This paper discussed the pathogenesis and the principle of treatment of the dry cough with yellow greasy coating. Combined the clinic observation with the TCM theory, we found that the main reasons about this dry cough are dryness in lung and stagnated phlegm. And heavy dosages herbs which can nourish Yin and clear away the heat should be adopted.
Intention to Create Legal Relations and the Reform of Contract Law: A Conservative Approach in the Modern Global Era  [PDF]
Zhixiong Liao
Beijing Law Review (BLR) , 2013, DOI: 10.4236/blr.2013.42011
Abstract: This paper is partially to refute the submissions by Gulati’s article recently published on Beijing Law Review which proposes abandoning the requirement of proving intention to create legal relations for the formation of an enforceable contract. After a critical analysis of the abandonists’ arguments, this paper argues that intention to create legal relations is the “marrow of contractual relationships” and the arguments for abandoning such a requirement because of the existence of consideration and/or offer and acceptance as test(s) of contractual enforceability is untenable and unconvincing. Consideration and/or offer and acceptance may be evidence of serious intention to be bound somehow but unnecessary intention to be bound legally. For a number of reasons, the doctrine of consideration is very unlikely to work any better than the intention to create legal relations test. If a test of contractual enforceability must be abandoned, that should be the doctrine of consideration rather than the intention to create legal relations. This paper compares the current positions of some common law jurisdictions, upholds the needs of stability, consistency, and the harmonisation of contract law in the modern global era, and proposes a conservative approach of contract law reform regarding the intention requirement and the related presumptions, that is, all common law jurisdictions should “go back” to the orthodox English position.
Data Fusion with Optimized Block Kernels in LS-SVM for Protein Classification  [PDF]
Li Liao
Engineering (ENG) , 2013, DOI: 10.4236/eng.2013.510B048
Abstract:

In this work, we developed a method to efficiently optimize the kernel function for combined data of various different sources with their corresponding kernels being already available. The vectorization of the combined data is achieved by a weighted concatenation of the existing data vectors. This induces a kernel matrix composed of the existing kernels as blocks along the main diagonal, weighted according to the corresponding the subspaces span by the data. The induced block kernel matrix is optimized in the platform of least-squares support vector machines simultaneously as the LS-SVM is being trained, by solving an extended set of linear equations, other than a quadratically constrained quadratic programming as in a previous method. The method is tested on a benchmark dataset, and the performance is significantly improved from the highest ROC score 0.84 using individual data source to ROC score 0.92 with data fusion.


Whether China’s State-Owned Commercial Banks Constitute “Public Bodies” within the Meaning of Article 1.1 (a) (1) of the Agreement on Subsidies and Countervailing Measures: Analysis of US—Definitive Anti-Dumping and Countervailing Duties on Certain Products from China  [PDF]
Yi Liao
Beijing Law Review (BLR) , 2013, DOI: 10.4236/blr.2013.44025
Abstract:

US—Definitive Anti-Dumping and Countervailing Duties on Certain Products from China is the initial WTO dispute in which China claims that US-countervailing duties on certain products from China are inconsistent with the obligations of the United States under the Agreement on Subsidies and Countervailing Measures (“SCM Agreement”). In this dispute, the specific meaning of “public bodies” within Article 1.1 (a) (1) of the SCM Agreement and the question of whether China’s state-owned commercial banks (“SOCB”) constitute “public bodies” are the heart of the matter. This thesis will analyze these issues by examining the reports of the Panel and the Appellate Body. In particular, the thesis will argue that the theory of the governmental function advanced by China is much more persuasive than that of governmental control in terms of defining “public bodies”. Although China’s SOCBs have gone through several stages of reforms, the majority ownership of them has remained in the hands of the Chinese government. However, SOCBs’ policy-oriented nature has been largely marginalized, and currently they only perform subsidiary governmental functions. In this regard, the conclusion this thesis will attempt to reach is that the WTO system needs to give developing countries like China more policy flexibility in order to upgrade their international trade participation to the level required and followed by developed countries. During the process, developing countries should also make the best use of their latent comparative advantage and the effects of globalization.

The Recent Amendment to China’s Consumer Law: An Imperfect Improvement and Proposal for Future Changes  [PDF]
Zhixiong Liao
Beijing Law Review (BLR) , 2014, DOI: 10.4236/blr.2014.53016
Abstract: Recently, an Amendment Act (“the Amendment”) was made to China’s core legislation on consumer protection—the Consumers’ Rights and Interests Protection Law (“Consumer Protection Act 1993”). The Amendment comes into force on China’s “Consumers’ Day” of 2014. The Amendment brings some great and significant changes to the principal Act in response to the need of China’s changed and changing market and society. This paper analyses the most significant changes and argues that the Amendment is far from being satisfactory, in that some important issues/problems including, inter alia, the want of a clear legal definition of “consumer”, are left unaddressed. It also articulates the rationale for special protection to consumer and proposes further amendments including a “good” definition of “consumer” that shall be adopted in the future as soon as practical.
Are Hong Kong Investors Interested in Shenzhen-Hong Kong Stock Connect
—An Investor Behavior Analysis Based on Shanghai-Hong Kong Stock Connect
 [PDF]

Xiaoyu Liao
Open Journal of Social Sciences (JSS) , 2016, DOI: 10.4236/jss.2016.43036
Abstract: In November 2014, Shenzhen-Hong Kong Stock Connect was opened. It has been more than one year until now. Although its transaction is not as expected, the opening of Shenzhen-Hong Kong Stock Connect is a must. Hong Kong investors investing in the A-share market in the Chinese mainland by Shenzhen-Hong Kong Stock Connect are mainly small- and medium-sized institutional investors who have not obtained QFII quota. Through the analysis of their investment behaviors, we have found that the preference of Hong Kong investors is single and concentrated. They extremely prefer financial blue-chip AH share. They will try to invest in growth stock in the unfamiliar A-share market, mainly mid cap stock with relatively high valuation, relatively low dividend, a certain risk and relatively good growth ability. They prefer information technology shares. The opening of Shenzhen-Hong Kong Stock Connect will bring opportunities different from those of Shenzhen-Hong Kong Stock Connect.
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